The Pfister house was built in 1537 for the hatter Ludwig Scherer, who made his fortune with money trading in the Val de Liepvre. Despite its medieval features, the house is the first example of architectural renaissance in Colmar. With its two-storey corner oriel, its wood gallery, its octagonal turret and its mural paintings which represent biblical and secular scenes, the Pfister house became one of the symbols of the old Colmar. It owns its name to the family who restored it and lived there from 1841 to 1892.
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